PART 01: EXECUTIVE SUMMARY PART 02: SCOPE OF THE REPORT 2.1 Preface 2.2 Preface 2.3 Currency conversion rates for US$ PART 03: MARKET LANDSCAPE Market ecosystem Market characteristics Market segmentation analysis PART 04: MARKET SIZING Market definition Market sizing 2018 Market size and forecast 2018-2023 PART 05: FIVE FORCES ANALYSIS Bargaining power of buyers Bargaining power of suppliers Threat of new entrants Threat of substitutes Threat of rivalry Market condition PART 06: PIPELINE ANALYSIS PART 07: MARKET SEGMENTATION BY TYPE Market segmentation by type Comparison by type ADPKD - Market size and forecast 2018-2023 ARPKD - Market size and forecast 2018-2023 Market opportunity by type PART 08: CUSTOMER LANDSCAPE PART 09: GEOGRAPHIC LANDSCAPE Geographic segmentation Geographic comparison North America - Market size and forecast 2018-2023 Europe - Market size and forecast 2018-2023 Asia - Market size and forecast 2018-2023 ROW - Market size and forecast 2018-2023 Key leading countries Market opportunity PART 10: DECISION FRAMEWORK PART 11: DRIVERS AND CHALLENGES Market drivers Market challenges PART 12: MARKET TRENDS Increasing research funding Favorable reimbursement policies Growing awareness about kidney diseases PART 13: VENDOR LANDSCAPE Overview Landscape disruption Competitive scenario PART 14: VENDOR ANALYSIS Vendors covered Vendor classification Market positioning of vendors Johnson & Johnson Services Inc. Merck & Co., Inc. Otsuka Holdings Co. Ltd. Reata Pharmaceuticals Inc. Sanofi PART 15: APPENDIX Research methodology List of abbreviations Definition of market positioning of vendors PART 16: EXPLORE TECHNAVIO Exhibit 01: Global pharmaceuticals market Exhibit 02: Segments of global pharmaceuticals market Exhibit 03: Market characteristics Exhibit 04: Market segments Exhibit 05: Market definition - Inclusions and exclusions checklist Exhibit 06: Market size 2018 Exhibit 07: Global market: Size and forecast 2018-2023 ($ millions) Exhibit 08: Global market: Year-over-year growth 2019-2023 (%) Exhibit 09: Five forces analysis 2018 Exhibit 10: Five forces analysis 2023 Exhibit 11: Bargaining power of buyers Exhibit 12: Bargaining power of suppliers Exhibit 13: Threat of new entrants Exhibit 14: Threat of substitutes Exhibit 15: Threat of rivalry Exhibit 16: Market condition - Five forces 2018 Exhibit 17: Some of the clinical stage drugs for polycystic kidney disease Exhibit 18: Type - Market share 2018-2023 (%) Exhibit 19: Comparison by type Exhibit 20: ADPKD - Market size and forecast 2018-2023 ($ millions) Exhibit 21: ADPKD - Year-over-year growth 2019-2023 (%) Exhibit 22: ARPKD - Market size and forecast 2018-2023 ($ millions) Exhibit 23: ARPKD - Year-over-year growth 2019-2023 (%) Exhibit 24: Market opportunity by type Exhibit 25: Customer landscape Exhibit 26: Market share by geography 2018-2023 (%) Exhibit 27: Geographic comparison Exhibit 28: North America - Market size and forecast 2018-2023 ($ millions) Exhibit 29: North America - Year-over-year growth 2019-2023 (%) Exhibit 30: Top 3 countries in North America Exhibit 31: Europe - Market size and forecast 2018-2023 ($ millions) Exhibit 32: Europe - Year-over-year growth 2019-2023 (%) Exhibit 33: Top 3 countries in Europe Exhibit 34: Asia - Market size and forecast 2018-2023 ($ millions) Exhibit 35: Asia - Year-over-year growth 2019-2023 (%) Exhibit 36: Top 3 countries in Asia Exhibit 37: ROW - Market size and forecast 2018-2023 ($ millions) Exhibit 38: ROW - Year-over-year growth 2019-2023 (%) Exhibit 39: Top 3 countries in ROW Exhibit 40: Key leading countries Exhibit 41: Market opportunity Exhibit 42: Prevalence of chronic kidney diseases per 100 people Exhibit 43: Impact of drivers and challenges Exhibit 44: Vendor landscape Exhibit 45: Landscape disruption Exhibit 46: Vendors covered Exhibit 47: Vendor classification Exhibit 48: Market positioning of vendors Exhibit 49: Johnson & Johnson Services Inc. - Vendor overview Exhibit 50: Johnson & Johnson Services Inc. - Business segments Exhibit 51: Johnson & Johnson Services Inc. - Organizational developments Exhibit 52: Johnson & Johnson Services Inc. - Geographic focus Exhibit 53: Johnson & Johnson Services Inc. - Segment focus Exhibit 54: Johnson & Johnson Services Inc. - Key offerings Exhibit 55: Johnson & Johnson Services Inc. - Key customers Exhibit 56: Merck & Co. Inc. - Vendor overview Exhibit 57: Merck & Co. Inc. - Business segments Exhibit 58: Merck & Co. Inc. - Organizational developments Exhibit 59: Merck & Co. Inc. - Geographic focus Exhibit 60: Merck & Co. Inc. - Segment focus Exhibit 61: Merck & Co. Inc. - Key offerings Exhibit 62: Merck & Co. Inc. - Key customers Exhibit 63: Otsuka Holdings Co. Ltd. - Vendor overview Exhibit 64: Otsuka Holdings Co. Ltd. - Business segments Exhibit 65: Otsuka Holdings Co. Ltd. - Organizational developments Exhibit 66: Otsuka Holdings Co. Ltd. - Geographic focus Exhibit 67: Otsuka Holdings Co. Ltd. - Segment focus Exhibit 68: Otsuka Holdings Co. Ltd. - Key offerings Exhibit 69: Otsuka Holdings Co. Ltd. - Key customers Exhibit 70: Reata Pharmaceuticals Inc. - Vendor overview Exhibit 71: Reata Pharmaceuticals Inc. - Organizational developments Exhibit 72: Reata Pharmaceuticals Inc. - Key offerings Exhibit 73: Reata Pharmaceuticals Inc. - Key customers Exhibit 74: Sanofi - Vendor overview Exhibit 75: Sanofi - Business segments Exhibit 76: Sanofi - Organizational developments Exhibit 77: Sanofi - Geographic focus Exhibit 78: Sanofi - Segment focus Exhibit 79: Sanofi - Key offerings Exhibit 80: Sanofi - Key customers Exhibit 81: Validation techniques employed for market sizing Exhibit 82: Definition of market positioning of vendors

Johnson & Johnson Services Inc. Merck & Co., Inc. Otsuka Holdings Co. Ltd. Reata Pharmaceuticals Inc. Sanofi.