Table of Contents Introduction Drug Addiction - Overview Drug Addiction - Therapeutics Development Drug Addiction - Therapeutics Assessment Drug Addiction - Companies Involved in Therapeutics Development Drug Addiction - Drug Profiles Drug Addiction - Dormant Projects Drug Addiction - Discontinued Products Drug Addiction - Product Development Milestones Appendix

List of Tables Number of Products under Development for Drug Addiction, H1 2019 Number of Products under Development by Companies, H1 2019 Number of Products under Development by Companies, H1 2019 (Contd..1), H1 2019 Number of Products under Development by Companies, H1 2019 (Contd..2), H1 2019 Number of Products under Development by Universities/Institutes, H1 2019 Products under Development by Companies, H1 2019 Products under Development by Companies, H1 2019 (Contd..1), H1 2019 Products under Development by Companies, H1 2019 (Contd..2), H1 2019 Products under Development by Universities/Institutes, H1 2019 Number of Products by Stage and Target, H1 2019 Number of Products by Stage and Target, H1 2019 (Contd..1), H1 2019 Number of Products by Stage and Mechanism of Action, H1 2019 Number of Products by Stage and Mechanism of Action, H1 2019 (Contd..1), H1 2019 Number of Products by Stage and Route of Administration, H1 2019 Number of Products by Stage and Molecule Type, H1 2019 Drug Addiction - Pipeline by Addex Therapeutics Ltd, H1 2019 Drug Addiction - Pipeline by Aelis Farma SAS, H1 2019 Drug Addiction - Pipeline by Aphios Corp, H1 2019 Drug Addiction - Pipeline by BioCorRx Inc, H1 2019 Drug Addiction - Pipeline by Charleston Laboratories Inc, H1 2019 Drug Addiction - Pipeline by Chiesi Farmaceutici SpA, H1 2019 Drug Addiction - Pipeline by Consegna Pharma Inc, H1 2019 Drug Addiction - Pipeline by Curemark LLC, H1 2019 Drug Addiction - Pipeline by Denovo Biopharma LLC, H1 2019 Drug Addiction - Pipeline by Egalet Corp, H1 2019 Drug Addiction - Pipeline by Embera NeuroTherapeutics Inc, H1 2019 Drug Addiction - Pipeline by F. Hoffmann-La Roche Ltd, H1 2019 Drug Addiction - Pipeline by Foresee Pharmaceuticals Co Ltd, H1 2019 Drug Addiction - Pipeline by IMV Inc, H1 2019 Drug Addiction - Pipeline by InterveXion Therapeutics LLC, H1 2019 Drug Addiction - Pipeline by Intra-Cellular Therapies Inc, H1 2019 Drug Addiction - Pipeline by KemPharm Inc, H1 2019 Drug Addiction - Pipeline by Kyorin Pharmaceutical Co Ltd, H1 2019 Drug Addiction - Pipeline by Kyowa Hakko Kirin Co Ltd, H1 2019 Drug Addiction - Pipeline by Novartis AG, H1 2019 Drug Addiction - Pipeline by Omeros Corp, H1 2019 Drug Addiction - Pipeline by Ovid Therapeutics Inc, H1 2019 Drug Addiction - Pipeline by P2D Inc, H1 2019List of Figures Number of Products under Development for Drug Addiction, H1 2019 Number of Products under Development by Companies, H1 2019 Number of Products under Development by Universities/Institutes, H1 2019 Number of Products by Top 10 Targets, H1 2019 Number of Products by Stage and Top 10 Targets, H1 2019 Number of Products by Top 10 Mechanism of Actions, H1 2019 Number of Products by Stage and Top 10 Mechanism of Actions, H1 2019 Number of Products by Top 10 Routes of Administration, H1 2019 Number of Products by Stage and Top 10 Routes of Administration, H1 2019 Number of Products by Top 10 Molecule Types, H1 2019 Number of Products by Stage and Top 10 Molecule Types, H1 2019

Addex Therapeutics Ltd Aelis Farma SAS Aphios Corp BioCorRx Inc Charleston Laboratories Inc Chiesi Farmaceutici SpA Consegna Pharma Inc Curemark LLC Denovo Biopharma LLC Egalet Corp Embera NeuroTherapeutics Inc F. Hoffmann-La Roche Ltd Foresee Pharmaceuticals Co Ltd IMV Inc InterveXion Therapeutics LLC Intra-Cellular Therapies Inc KemPharm Inc Kyorin Pharmaceutical Co Ltd Kyowa Hakko Kirin Co Ltd Novartis AG Omeros Corp Ovid Therapeutics Inc P2D Inc Protagenic Therapeutics Inc Saniona AB Sosei Heptares SpringWorks Therapeutics LLC Zynerba Pharmaceuticals Inc