PART 01: EXECUTIVE SUMMARY PART 02: SCOPE OF THE REPORT • 2.1 Preface • 2.2 Preface • 2.3 Currency conversion rates for US$ PART 03: MARKET LANDSCAPE • Market ecosystem • Market characteristics • Market segmentation analysis PART 04: MARKET SIZING • Market definition • Market sizing 2018 • Market size and forecast 2018-2023 PART 05: FIVE FORCES ANALYSIS • Bargaining power of buyers • Bargaining power of suppliers • Threat of new entrants • Threat of substitutes • Threat of rivalry • Market condition PART 06: MARKET SEGMENTATION BY TYPE • Market segmentation by type • Comparison by type • Cryotherapy - Market size and forecast 2018-2023 • Electrocautery - Market size and forecast 2018-2023 • Other treatments - Market size and forecast 2018-2023 • Market opportunity by type PART 07: CUSTOMER LANDSCAPE PART 08: GEOGRAPHIC LANDSCAPE • Geographic segmentation • Geographic comparison • North America - Market size and forecast 2018-2023 • Europe - Market size and forecast 2018-2023 • Asia - Market size and forecast 2018-2023 • ROW - Market size and forecast 2018-2023 • Market opportunity PART 09: DRIVERS AND CHALLENGES • Market drivers • Market challenges PART 10: MARKET TRENDS PART 11: VENDOR LANDSCAPE • Overview • Landscape disruption • Competitive scenario PART 12: VENDOR ANALYSIS • Vendors covered • Vendor classification • Market positioning of vendors • Aclaris Therapeutics, Inc. • Brymill Cryogenic Systems • CryoConcepts LP • OLYMPUS CORPORATION • Special Medical Technology Co., Ltd. PART 13: APPENDIX • Research methodology • List of abbreviations   Exhibit 01: Global pharmaceuticals market Exhibit 02: Segments of global pharmaceuticals market Exhibit 03: Market characteristics Exhibit 04: Market segments Exhibit 05: Market definition - Inclusions and exclusions checklist Exhibit 06: Market size 2018 Exhibit 07: Global market: Size and forecast 2018-2023 ($ millions) Exhibit 08: Global market: Year-over-year growth 2019-2023 (%) Exhibit 09: Five forces analysis 2018 Exhibit 10: Five forces analysis 2023 Exhibit 11: Bargaining power of buyers Exhibit 12: Bargaining power of suppliers Exhibit 13: Threat of new entrants Exhibit 14: Threat of substitutes Exhibit 15: Threat of rivalry Exhibit 16: Market condition - Five forces 2018 Exhibit 17: - Market share 2018-2023 (%) Exhibit 18: Comparison by type Exhibit 19: Cryotherapy - Market size and forecast 2018-2023 ($ millions) Exhibit 20: Cryotherapy - Year-over-year growth 2019-2023 (%) Exhibit 21: Electrocautery - Market size and forecast 2018-2023 ($ millions) Exhibit 22: Electrocautery - Year-over-year growth 2019-2023 (%) Exhibit 23: Other treatments - Market size and forecast 2018-2023 ($ millions) Exhibit 24: Other treatments - Year-over-year growth 2019-2023 (%) Exhibit 25: Market opportunity by type Exhibit 26: Customer landscape Exhibit 27: Market share by geography 2018-2023 (%) Exhibit 28: Geographic comparison Exhibit 29: North America - Market size and forecast 2018-2023 ($ millions) Exhibit 30: North America - Year-over-year growth 2019-2023 (%) Exhibit 31: Top 3 countries in North America Exhibit 32: Europe - Market size and forecast 2018-2023 ($ millions) Exhibit 33: Europe - Year-over-year growth 2019-2023 (%) Exhibit 34: Top 3 countries in Europe Exhibit 35: Asia - Market size and forecast 2018-2023 ($ millions) Exhibit 36: Asia - Year-over-year growth 2019-2023 (%) Exhibit 37: Top 3 countries in Asia Exhibit 38: ROW - Market size and forecast 2018-2023 ($ millions) Exhibit 39: ROW - Year-over-year growth 2019-2023 (%) Exhibit 40: Top 3 countries in ROW Exhibit 41: Market opportunity Exhibit 42: Growth in geriatric population 2013-2017 (%) Exhibit 43: Impact of drivers and challenges Exhibit 44: Vendor landscape Exhibit 45: Landscape disruption Exhibit 46: Vendors covered Exhibit 47: Vendor classification Exhibit 48: Market positioning of vendors Exhibit 49: Aclaris Therapeutics, Inc. - Vendor overview Exhibit 50: Aclaris Therapeutics, Inc. - Business segments Exhibit 51: Aclaris Therapeutics, Inc. - Organizational developments Exhibit 52: Aclaris Therapeutics, Inc. - Segment focus Exhibit 53: Aclaris Therapeutics, Inc. - Key offerings Exhibit 54: Aclaris Therapeutics, Inc. - Key customers Exhibit 55: Brymill Cryogenic Systems - Vendor overview Exhibit 56: Brymill Cryogenic Systems - Key offerings Exhibit 57: Brymill Cryogenic Systems - Key customers Exhibit 58: CryoConcepts LP - Vendor overview Exhibit 59: CryoConcepts LP - Key offerings Exhibit 60: CryoConcepts LP - Key customers Exhibit 61: OLYMPUS CORPORATION - Vendor overview Exhibit 62: OLYMPUS CORPORATION - Business segments Exhibit 63: OLYMPUS CORPORATION - Organizational developments Exhibit 64: OLYMPUS CORPORATION - Geographic focus Exhibit 65: OLYMPUS CORPORATION - Segment focus Exhibit 66: OLYMPUS CORPORATION - Key offerings Exhibit 67: OLYMPUS CORPORATION - Key customers Exhibit 68: Special Medical Technology Co., Ltd. - Vendor overview Exhibit 69: Special Medical Technology Co., Ltd. - Key offerings Exhibit 70: Special Medical Technology Co., Ltd. - Key customers Exhibit 71: Validation techniques employed for market sizing

Aclaris Therapeutics, Inc. Brymill Cryogenic Systems CryoConcepts LP OLYMPUS CORPORATION Special Medical Technology Co., Ltd.