PART 01: EXECUTIVE SUMMARY PART 02: SCOPE OF THE REPORT • 2.1 Preface • 2.2 Preface • 2.3 Currency conversion rates for US$ PART 03: MARKET LANDSCAPE • Market ecosystem • Market characteristics • Market segmentation analysis PART 04: MARKET SIZING • Market definition • Market sizing 2018 • Market size and forecast 2018-2023 PART 05: FIVE FORCES ANALYSIS • Bargaining power of buyers • Bargaining power of suppliers • Threat of new entrants • Threat of substitutes • Threat of rivalry • Market condition PART 06: MARKET SEGMENTATION BY PRODUCT • Market segmentation by product • Comparison by product • Heart valve replacement devices - Market size and forecast 2018-2023 • Heart valve repair devices - Market size and forecast 2018-2023 • Market opportunity by product PART 07: MARKET SEGMENTATION BY SURGERY • Market segmentation by surgery • Comparison by surgery • Minimally invasive surgeries - Market size and forecast 2018-2023 • Transcatheter surgeries - Market size and forecast 2018-2023 • Open surgeries - Market size and forecast 2018-2023 • Market opportunity by surgery PART 08: CUSTOMER LANDSCAPE PART 09: GEOGRAPHIC LANDSCAPE • Geographic segmentation • Geographic comparison • North America - Market size and forecast 2018-2023 • Europe - Market size and forecast 2018-2023 • Asia - Market size and forecast 2018-2023 • ROW - Market size and forecast 2018-2023 • Key leading countries • Market opportunity PART 10: DECISION FRAMEWORK PART 11: DRIVERS AND CHALLENGES • Market drivers • Market challenges PART 12: MARKET TRENDS • Technological advances • Development of heart valve with tissue engineering approach • Industry developments PART 13: VENDOR LANDSCAPE • Overview • Landscape disruption PART 14: VENDOR ANALYSIS • Vendors covered • Vendor classification • Market positioning of vendors • Abbott • Boston Scientific Corporation • CryoLife, Inc • Edwards Lifesciences Corporation • LivaNova PLC • Medtronic PART 15: APPENDIX • Research methodology • List of abbreviations PART 16: EXPLORE TECHNAVIO   Exhibit 01: Global medical devices market Exhibit 02: Segments of global medical devices market Exhibit 03: Market characteristics Exhibit 04: Market segments Exhibit 05: Market definition - Inclusions and exclusions checklist Exhibit 06: Market size 2018 Exhibit 07: Global market: Size and forecast 2018-2023 ($ millions) Exhibit 08: Global market: Year-over-year growth 2019-2023 (%) Exhibit 09: Five forces analysis 2018 Exhibit 10: Five forces analysis 2023 Exhibit 11: Bargaining power of buyers Exhibit 12: Bargaining power of suppliers Exhibit 13: Threat of new entrants Exhibit 14: Threat of substitutes Exhibit 15: Threat of rivalry Exhibit 16: Market condition - Five forces 2018 Exhibit 17: Product - Market share 2018-2023 (%) Exhibit 18: Comparison by product Exhibit 19: Heart valve replacement devices - Market size and forecast 2018-2023 ($ millions) Exhibit 20: Heart valve replacement devices - Year-over-year growth 2019-2023 (%) Exhibit 21: Heart valve repair devices - Market size and forecast 2018-2023 ($ millions) Exhibit 22: Heart valve repair devices - Year-over-year growth 2019-2023 (%) Exhibit 23: Market opportunity by product Exhibit 24: Surgery - Market share 2018-2023 (%) Exhibit 25: Comparison by surgery Exhibit 26: Minimally invasive surgeries - Market size and forecast 2018-2023 ($ millions) Exhibit 27: Minimally invasive surgeries - Year-over-year growth 2019-2023 (%) Exhibit 28: Transcatheter surgeries - Market size and forecast 2018-2023 ($ millions) Exhibit 29: Transcatheter surgeries - Year-over-year growth 2019-2023 (%) Exhibit 30: Open surgeries - Market size and forecast 2018-2023 ($ millions) Exhibit 31: Open surgeries - Year-over-year growth 2019-2023 (%) Exhibit 32: Market opportunity by surgery Exhibit 33: Customer landscape Exhibit 34: Market share by geography 2018-2023 (%) Exhibit 35: Geographic comparison Exhibit 36: North America - Market size and forecast 2018-2023 ($ millions) Exhibit 37: North America - Year-over-year growth 2019-2023 (%) Exhibit 38: Europe - Market size and forecast 2018-2023 ($ millions) Exhibit 39: Europe - Year-over-year growth 2019-2023 (%) Exhibit 40: Asia - Market size and forecast 2018-2023 ($ millions) Exhibit 41: Asia - Year-over-year growth 2019-2023 (%) Exhibit 42: ROW - Market size and forecast 2018-2023 ($ millions) Exhibit 43: ROW - Year-over-year growth 2019-2023 (%) Exhibit 44: Key leading countries Exhibit 45: Market opportunity Exhibit 46: Impact of drivers and challenges Exhibit 47: Vendor landscape Exhibit 48: Landscape disruption Exhibit 49: Vendors covered Exhibit 50: Vendor classification Exhibit 51: Market positioning of vendors Exhibit 52: Abbott - Vendor overview Exhibit 53: Abbott - Business segments Exhibit 54: Abbott - Organizational developments Exhibit 55: Abbott - Geographic focus Exhibit 56: Abbott - Segment focus Exhibit 57: Abbott - Key offerings Exhibit 58: Boston Scientific Corporation - Vendor overview Exhibit 59: Boston Scientific Corporation - Business segments Exhibit 60: Boston Scientific Corporation - Organizational developments Exhibit 61: Boston Scientific Corporation - Geographic focus Exhibit 62: Boston Scientific Corporation - Segment focus Exhibit 63: Boston Scientific Corporation - Key offerings Exhibit 64: CryoLife, Inc - Vendor overview Exhibit 65: CryoLife, Inc - Business segments Exhibit 66: CryoLife, Inc - Organizational developments Exhibit 67: CryoLife, Inc - Geographic focus Exhibit 68: CryoLife, Inc - Segment focus Exhibit 69: CryoLife, Inc - Key offerings Exhibit 70: Edwards Lifesciences Corporation - Vendor overview Exhibit 71: Edwards Lifesciences Corporation - Product segments Exhibit 72: Edwards Lifesciences Corporation - Organizational developments Exhibit 73: Edwards Lifesciences Corporation - Geographic focus Exhibit 74: Edwards Lifesciences Corporation - Segment focus Exhibit 75: Edwards Lifesciences Corporation - Key offerings Exhibit 76: LivaNova PLC - Vendor overview Exhibit 77: LivaNova PLC - Business segments Exhibit 78: LivaNova PLC - Organizational developments Exhibit 79: LivaNova PLC - Geographic focus Exhibit 80: LivaNova PLC - Segment focus Exhibit 81: LivaNova PLC - Key offerings Exhibit 82: Medtronic - Vendor overview Exhibit 83: Medtronic - Business segments Exhibit 84: Medtronic - Organizational developments Exhibit 85: Medtronic - Geographic focus Exhibit 86: Medtronic - Segment focus Exhibit 87: Medtronic - Key offerings Exhibit 88: Validation techniques employed for market sizing

Abbott Boston Scientific Corporation CryoLife, Inc. Edwards Lifesciences Corporation LivaNova PLC Medtronic